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Description

Uses of Tramadol 50mg

People can buy Tramadol 50mg online to help relieve moderate to severe pain. Its extended delivery formulation can also help with longer-lasting pain conditions occurring due to chronic illness such as cancer.

Tramadol 50mg pills contain a 50 milligrams dose of the Tramadol HCL salt in a conventional tablet form. It comes in different colors with various imprints on it.

You can buy Tramadol 50mg online from a certified pharmacy like us without fearing the risk of getting fake medicines.

Side effects of Tramadol 50mg

Tramadol is an opioid analgesic, and it may produce some side effects. The most frequent Tramadol 50mg side effects include:

Dizziness
Sweating
Nausea
Dry mouth
Vomiting

Other side effects include fatigue, somnolence, asthenia, flushing, constipation, confusion, vertigo, headache, palpitations, tachycardia, insomnia, miosis, seizures, orthostatic hypotension, and central nervous system simulations, including hallucinations and respiratory depression.

Tramadol 50mg Medication Interactions

Conceivable increase in anticoagulation with warfarin.
Increased risk of seizures with TCA and SSRIs.
Increased risk of serotonin syndrome with mirtazapine, venlafaxine, SSRIs, and MAOIs
Tramadol should not be given to patients receiving MAOIs or within 14 days of their discontinuation.
Decreased analgesic efficacy of tramadol with carbamazepine, 5-ht3-receptor antagonist, e.g., ondansetron.
Increased respiratory and CNS depression with CNS depressants, e.g., liquor, opioids, anesthetic agents, narcotics, phenothiazines, tranquilizer, or sedative-hypnotics.

Contraindications of Tramadol 50mg

Patients with the following issues should not use the medication or buy Tramadol 50mg online only when prescribed by a certified medical professional:

Acute alcoholism
Suicidal thoughts or ideation
Raised intracranial pressure
Head injuries
Lactation
Severe renal impairment

Action Mechanism

Tramadol 50mg inhibits the reuptake of norepinephrine, serotonin and enhances serotonin release. The medication alters perception and response to pain by binding to mu-opiate receptors in the central nervous system.

Initiation of action: oral (conventional tablet): 1 hr. span: oral (conventional tablet): 3-6 hr. Assimilation: readily absorbed from the gi tract (oral).

Dissemination: widely distributed. It cuts across the placenta and enters breast milk.

Digestion: extensive hepatic first-pass metabolism; converted to o-desmethyl tramadol (active) by n-and o-demethylation via the cytochrome p450 isoenzymes cyp3a4 and cyp2d6 and glucuronidation or sulfation.

Discharge: via urine (as metabolites); 6 hr (elimination half-life).